Linezolid Impurity 27

Linezolid Impurity 27 - Names and Identifiers

Name	4-(2-Fluoro-4-nitrophenyl)morpholine
Synonyms	Linezolid Impurity 27 Linezolid Impurity 12 4-(2-fluoro-nitrophenyl)Morpholine N-(2-Fluoro-4-nitrophenyl)morpholine 4-(2-Fluoro-4-nitrophenyl)morpholine 4-(2-Fluoro-4-Nitro-Phenyl)-Morpholine 3-fluoro-4-(4-morpholinyl)nitrobenzene 4-(2-FLUORO-4-NITRO-PHENYL)-MORPHOLINE 4-(2-fluoro-4-nitrophenyl) Moropholine Morpholine, 4-(2-fluoro-4-nitrophenyl)- 3-Fluoro-4-(4-morpholinyl) nitrobenzene (FMN)
CAS	2689-39-6
EINECS	1592732-453-0
InChI	InChI=1/C10H11FN2O3/c11-9-7-8(13(14)15)1-2-10(9)12-3-5-16-6-4-12/h1-2,7H,3-6H2

Linezolid Impurity 27 - Physico-chemical Properties

Molecular Formula	C10H11FN2O3
Molar Mass	226.2
Density	1.340±0.06 g/cm3(Predicted)
Melting Point	121-126℃
Boling Point	380.9±42.0 °C(Predicted)
Flash Point	184.2°C
Solubility	Chloroform (Slightly), Methanol (Slightly)
Vapor Presure	5.26E-06mmHg at 25°C
Appearance	Solid
Color	Yellow to Orange
pKa	0.62±0.40(Predicted)
Storage Condition	2-8°C
Refractive Index	1.56

Linezolid Impurity 27 - Risk and Safety

Hazard Symbols

Xi - Irritant

Linezolid Impurity 27 - Introduction

4-(2-Fluoro-4-nitrophenyl)morpholine is an organic compound with the chemical formula C10H10FNO3. Its structure contains a 4-morpholinobenzene ring with fluorine atoms and nitro groups substituted on the benzene ring.

Nature:
4-(2-Fluoro-4-nitrophenyl)morpholine is a white crystal or crystalline powder with a high melting point and boiling point. It is almost insoluble in water at normal temperature, but soluble in organic solvents such as ethanol, dimethyl ether and methylene chloride. It is a stable compound that does not readily decompose or degrade under normal storage conditions.

Use:
4-(2-Fluoro-4-nitrophenyl)morpholine is commonly used as an intermediate in organic synthesis and has important applications in the synthesis of pesticides and drugs. It can also be used in the production of chemicals for the dye, photosensitizer and rubber industries. In addition, it can also be used as a raw material for the synthesis of organic materials.

Method:
The preparation of 4-(2-Fluoro-4-nitrophenyl)morpholine can usually be obtained by reacting acetophenone with diethyl 3-fluoro-4-nitrophenylborate in the presence of an oxidizing agent.

Safety Information:
Since 4-(2-Fluoro-4-nitrophenyl)morpholine is an organic compound, it may cause certain harm to the human body. In use or operation, should strictly follow the relevant safety procedures, and take appropriate protective measures, such as wearing gloves, masks and protective glasses. Avoid contact with skin and eyes, and do not breathe its dust or gas. If you are exposed or ingested, you should seek medical treatment immediately and bring your safety data sheet with you for your doctor's reference.

Last Update：2024-04-09 21:04:16